Search 145 biotransformation reactions by:
The database is primarily set up to provide interesting or instructional examples
of the many and various different types of biotransformations encountered in drug
It is not an exhaustive catalogue of the metabolism of each functional group or
Click the tab to search the database.
If you have plasma clearance data from at least three species, this application
will predict human plasma clearance by allometric scaling.
The application generates a full report (abstract, introduction,
methods, results, discussion) for you.
The scaling is based on the algorithm of
Mahmood and Balian (1996)
and the liver
blood flow method of
Ward and Smith (2004).
Click the tab to find out more and try the application.
This application will calculate the molecular mass, accurate to six decimal places,
of a molecule based on it's empirical formula.
The mass calculated is the monoisotopic mass based on the most abundant naturally
occuring isotope of each atom.
Click the tab to try it out.
Useful links related to drug metabolism with a brief description about them.
Click the tab to go to the links page.
Books related to drug metabolism, mass spectrometry, NMR, HPLC, toxicology and drug development
Click the tab to go to the books page.
How easy is it to find information about drug metabolism on the internet?
Not so easy is the answer. Click here
to read more!
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